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semax5

Semax 5MG

ACTH (4-10)ACTH (4-7)-Pro-Gly-ProMet-Glu-His-Phe-Pro-Gly-ProMEHFPGP
A 7-amino acid synthetic heptapeptide analog of ACTH (4-10) that upregulates BDNF expression and modulates the TrkB signaling pathway, studied for cognitive enhancement and neuroprotection in clinical research.

$30.00

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๐Ÿง 
1.0ร—
BDNF Increase
Brain-derived neurotrophic factor
๐Ÿ”ฌ
7
Amino Acids
ACTH(4-10) synthetic analog
๐Ÿฅ
2011
Approved in Russia
Prescription nootropic since 2011
โœ…
99%+
Purity Verified
HPLC tested, COA included

How It Works

Neuropeptide derived from ACTH with cognitive-enhancing and neuroprotective properties

Neurotrophic

BDNF Modulation

Semax increases brain-derived neurotrophic factor (BDNF) levels by up to 1.4-fold in specific brain regions, supporting neuronal survival, growth, and synaptic plasticity.

  • Increases BDNF expression up to 1.4ร—
  • Supports neuronal survival and growth
  • Enhances synaptic plasticity
Neurotransmitter

Serotonin & Dopamine Modulation

Research demonstrates Semax modulates serotonergic and dopaminergic systems, influencing mood regulation, attention, and cognitive processing in preclinical models.

  • Modulates serotonin metabolism
  • Influences dopaminergic signaling
  • Affects noradrenergic pathways
Neuroprotective

Ischemic Protection

In ischemic stroke models, Semax demonstrates neuroprotective effects by reducing infarct volume, modulating inflammatory gene expression, and promoting neuronal survival under oxygen deprivation.

  • Reduces infarct volume in stroke models
  • Anti-inflammatory gene modulation
  • Protects neurons from oxidative stress
๐Ÿ“Š

What Research Has Shown

Key findings from preclinical and clinical studies

BDNF Expression Increase 140%
Cognitive Performance (animal) 65%
Neuroprotection (ischemia) 78%
Anti-Inflammatory Effect 60%
๐ŸŽฏ

Research Applications

Primary areas of investigation

COGNITIVE

Memory & Learning

Enhances cognitive function, memory consolidation, and attention in animal models. Approved as a nootropic in Russia since 2011.

Ashmarin et al. 2006 โ†—
NEUROPROTECTION

Stroke Recovery

Reduces ischemic brain damage and promotes neuronal survival in cerebral ischemia models. Used clinically in Russia for stroke recovery.

Gusev et al. 2010 โ†—
NEUROTROPHIC

BDNF & Nerve Growth

Modulates expression of neurotrophins and their receptors, supporting neuronal plasticity and regeneration pathways.

Agapova et al. 2010 โ†—
ANTI-INFLAMMATORY

Immune Modulation

Reduces pro-inflammatory cytokines and modulates oxidative stress-related gene expression in hippocampal tissue.

Agapova et al. 2011 โ†—
๐Ÿงช

Compound Information

Technical specifications

Sequence Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Weight 813.93 Da
Molecular Formula C37H51N9O10S

Precision research compounds backed by quality, transparency, and consistency.
Research Without Compromise.

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